Buffalo Bill's House
Buffalo Bill's House, 8 Circle St, Perryopolis, PA 15473, USA
About
Buffalo Bill’s House in Perryopolis, PA is the actual Silence of the Lambs filming location... and yes, you can stay overnight. It’s a private rental, so you get the whole house, including the basement with the recreated well that movie fans will immediately recognize. It’s equal parts iconic and slightly unsettling, and definitely not your standard weekend stay.